- 种康
- 研究员

种康,男,博士,研究员/教授,博士生导师;中国科学院院士。 |
中国科学院院士,植物分子发育生理研究组组长、NSFC国家杰出青年获得者、NSFC“细胞分化与器官发生”创新群体首席科学家、“百千万人才工程”国家级人选。中国科学院植物研究所党委书记、副所长,中国科学院大学教授。社会兼职有国际植物生物技术联合会中国分会负责人、中国植物学会理事长和植物生理与分子生物学会理事。担任《植物学报》主编,JBC、Plant Cell Reports、MGG等国际学术期刊编委。主持承担多项国家重大项目,如国家战略性先导专项项目、973和863项目等。迄今在Cell、Nature Communications、PNAS、Developmental Cell、EMBO J、The Plant Cell等国际主流学术期刊发表研究论文60余篇。多次获得中国科学院优秀教师奖励。已培养硕士和博士40余名和博士后5名,其中多名博士生获得“中国科学院优秀博士论文”奖励和中国科学院院长优秀奖。毕业生中有24名在国外从事博士后研究或工作,其中在美国和国内教授职位5名。 主要研究工作: 1. 小麦开花与春化作用分子机理 发现植物感知春化信号机制,阐明春化过程中,类凝集素VER2的磷酸化修饰与RNA结合蛋白GRP2的糖基化修饰控制春化基因VRN1的RNA剪切介导开花的分子网络机制。 2. 水稻感受低温信号的分子应答机制 发现水稻低温感受复合物及其作用机制,揭示了水稻在人工驯化过程中,耐寒性关键基因起源于中国野生稻。 3. 水稻激素信号互作调控器官发生的分子网络 揭示植物激素独脚金内酯和甾醇类激素控制水稻侧芽分化与叶角控制的基因网络新机制。 主持和参加的科研项目: [1] “水稻温度耐受的分子模块解析”,中国科学院先导专项项目(2013.07-2018.08);主持人种康 [2] “水稻稳产性状的分子机制与设计”,科技部973课题(2013.01-2017.12);主持人种康 [3]“作物感知冷信号的机制”,院国际合作项目(2017.01-2019.12);主持人种康 [4] “水稻产量相关基因克隆与功能研究”,科技部“十三五”重点研发计划(2016.07-2020.12);主持人种康 研究论文(注*为通讯作者,§为共同第一作者): 2018 Xing LJ§, Liu Y§, Xu SJ, Xiao J, Wang B, Deng HW, Lu Z, Xu YY, Chong K*. 2018. Arabidopsis O-GlcNAc transferase SEC activates histone methyltransferase ATX1 to regulate flowering. EMBO J., 37: e98115. Xu SJ, Chong K*. 2018, Remembering winter through vernalisation. Nat. Plants, 4: 997-1009 Chen LP, Zhao Y, Xu SJ, Zhang ZY, Xu YY, Zhang JY, Chong K*. 2018. OsMADS57 together with OsTB1 coordinates transcription of its target OsWRKY94 and D14 to switch its organogenesis to defense for cold adaptation in rice. New Phytol., 218: 219-231. 2017 Zhang ZY, Li JH, Li F, Liu HH, Yang WS, Chong K and Xu YY. 2017. OsMAPK3 phosphorylates OsbHLH002/OsICE1 and inhibits its ubiquitination to activate OsTPP1 and enhances rice chilling tolerance. Developmental Cell, 43:731–743. Guo XY, Xu SJ, Chong K. 2017. Cold signal shuttles from membrane to nucleus.Molecular Cell., 66:7-8. 2016 Zhang JY, Luo W, Zhao Y, Xu YY, Song SH, Chong K. 2016. Comparative metabolomic analysis reveals a reactive oxygen species-dominated dynamic model underlying chilling environment adaptation and tolerance in rice. New Phytologist, 211: 1295-1310. 2015 Ma Y*, Dai XY*, Xu YY*, Luo W*, Zheng XM, Zeng DL, Pan YJ, Lin XL, Liu HH, Zhang DJ, Xiao J, Guo XY, Xu SJ, Niu YD, Jin JB, Zhang H, Xu X, Li LG, Wang W, Qian Q, Ge S, Chong K. 2015. COLD1 confers chilling tolerance in rice. Cell, 160: 1209-1221(*These authors contributed equally to this Work). Wang L, Chong K. 2015. The essential role of cytokin in signaling in root apical meristem formation during somatic embryogenesis. Frontiers in Plant Science, 6: 1196-1200. 2014 Xiao J, Xu SJ, Li CH, Xu YY, Xing LJ, Niu YD Huan Q, Tang Y, Zhao CP, Wagner D, Gao CX, Chong K. 2014. O-GlcNAc-mediated interaction between VER2 and TaGRP2 elicits TaVRN1 mRNA accumulation during vernalization in winter wheat. Nature Communications, 5: 4572. Chong K and Xu ZH. 2014. Investment in plant research and development bears fruit in China. Plant Cell Reports, 33: 541-550. Liu HH, Ma Y, Chen N, Guo SY, Liu HL, Guo XY, Chong K, Xu YY*. 2014. Overexpression of stress-inducible OsBURP16, the β subunit of polygalacturonase 1, decreases pectin content and cell adhesion and increases abiotic stress sensitivity in rice. Plant Cell Environ, 37: 1144–1158. Liu HH, Guo SY, Xu YY, Li CH, Zhang ZY, Zhang DJ, Xu SJ, Zhang C, Chong K*. 2014. OsmiR396d-regulated OsGRFs Function in Floral Organogenesis in Rice through Binding to their Targets OsJMJ706 and OsCR4. Plant Physiol, 165:160-174. 2013 Zhang JY, Mao ZW and Chong K. 2013. A global profiling of uncapped mRNAs under cold stress reveals specific decay patterns and endonucleolytic cleavages in Brachypodium distachyon. Genome Biology. 14:R92. Zhang YY, Li BB, Xu YY, Li HL, Li SS, Zhang DJ, Mao ZW, Guo SY, Yang CH, Weng YX, and Chong K. 2013. The Cyclophilin CYP20-2 Modulates the Conformation of BRASSINAZOLE - RESISTANT1, Which Binds the Promoter of FLOWERING LOCUS D to Regulate Flowering in Arabidopsis. The Plant Cell. 25:2504-2521. Chen Y, Xu YY, Luo W, Li WX, Chen N, Zhang DJ and Chong K. 2013. The F-box protein OsFBK12 targets OsSAMS1 for degradation and affects pleiotropic phenotypes including leaf senescence in rice. Plant Physiology. 163:1673-1685. Guo SY, Xu YY, Liu HL, Mao ZW, Zhang C, Ma Y, Zhang QR, Meng Z and Chong K. 2013. The interaction between OsMADS57 and OsTB1 modulates rice tillering via DWARF14. Nature Communications.4:1566-1574. 2012 Li CJ, Liu ZJ, Zhang QR, Wang R, Xiao LT, Ma H, Chong K and Xu YY. 2012. SKP1 is involved in abscisic acid signalling to regulate seed germination, stomatal opening and root growth in Arabidopsis thaliana. Plant Cell and Environment, 35, 952–965 Zhang C, Xu YY, Guo SY, Zhu J, Huan Q, Liu HL, Wang L, Luo GZ, Wang XJ and Chong K. 2012. Dynamics of brassinosteroid response modulated by negative regulator LIC in rice. PLoS Genetics, 8: e1002686 2011 Li J, Jiang JF, Qian Q, Xu YY, Zhang C, Xiao J, Du C, Luo W, Zou GX, Chen ML, Huang YQ, Feng YQ, Cheng ZK, Yuan M and Chong K. 2011. Mutation of rice BC12/GDD1, which encodes a kinesin-like protein that binds to a GA biosynthesis gene promoter, leads to dwarfism with impaired cell elongation. The Plant Cell, 2: 628-640 Cao H, Guo SY, Xu YY, Jiang K, Jones AM and Chong K. 2011. Reduced expression of a gene encoding a Golgi localized monosaccharide transporter (OsGMST1) confers hypersensitivity to salt in rice (Oryza sativa). Journal of Experimental Botany, 62:4595-4604 Chen N, Xu YY, Wang X, Du C, Du JZ, Yuan M, Xu ZH and Chong K. 2011. OsRAN2, essential for mitosis, enhances cold tolerance in rice by promoting export of intranuclear tubulin and maintaining cell division under cold stress. Plant Cell and Environment, 34:52-64 2010及以前 Li BB, Xu WZ, Xu YY, Zhang YY, Wang T, Bai Y, Han CG, Zhang AM, Xu ZH and Chong K. 2010. Integrative study on proteomics, molecular physiology and genetics reveals an accumulation of cyclophilin-like protein, TaCYP20-2, leads to increase of Rht protein and dwarf in a novel GA-insensitive mutant (gaid) in wheat. Journal of Proteome Research, 8:4242–4253 Xing LJ, Li J, Xu YY, Xu ZH and Chong K. 2009. Phosphorylation modification of wheat lectin VER2 is associated with vernalization-induced O-GlcNAc signaling and intracellular motility. PLoS ONE, 4: e4854 Wang L, Wang Z, Xu YY, Joo SH, Kim SK, Xue Z, Xu ZH, Wang ZY and Chong K. 2009. OsGSR1 is involved in cross-talk between gibberellins and brassinosteroids in rice. The Plant Journal, 57: 498-510 Li D, Wang L, Wang M, Xu YY, Luo W, Liu YJ, Xu ZH, Li J and Chong K. 2009. Engineering OsBAK1 gene as a molecular tool to improve rice architecture for high yield. Plant Biotechnology Journal, 7:791–806 Ma QB, Dai XY, Xu YY, Guo J, Liu YJ, Chen N, Xiao J, Zhang DJ, Xu ZH, Zhang XS and Chong K. 2009. Enhanced tolerance to chilling stress in OsMYB3R-2 transgenic rice is mediated by alteration in cell cycle and ectopic expression of stress genes. Plant Physiology, 150: 244-256 Han Y, Cao H, Jiang JF, Xu YY, Du JZ, Wang X, Yuan M, Wang ZY, Xu ZH and Chong K. 2008. The rice ROOT ARCHITECTURE ASSOCIATED1 binds the proteasome subunit RPT4 and is degraded in a D-box and proteasome dependent manner. Plant Physiology, 148: 843-855 Wang X, Zhang Y, Ma QB, Zhang ZL, Xue YB, Bao SL and Chong K. 2007. SKB1-mediated symmetric dimethylation of histone H4R3 controls flowering time in Arabidopsis. The EMBO Journal, 26: 1934-1941 Zhuang XL, Jiang JF, Li J, Ma QB, Xu YY, Xue YB, Xu ZH and Chong K. 2006. Overexpression of OsAGAP, an ARF-GAP, interferes with auxin influx, vesicle trafficking and root development. The Plant Journal, 48: 581-591 Wang X, Xu YY, Han Y, Bao SL, Du J, Yuan M, Xu ZH and Chong K. 2006. Overexpression of RAN1 in rice and Arabidopsis alters primordial meristem, mitotic progress and sensitivity to auxin. Plant Physiology, 140: 91-101 Wang Z, Liang Y, Li CJ, Xu YY, Lan LF, Chen CJ, Xu ZH, Xue YB and Chong K. 2005. Identification of another development-related genes by gene expression profiling with a 10-K cDNA microarray in rice (Oryza sativa L. ). Plant Molecular Biology, 58: 721-737 Zhuang XL, Xu YY, Chong K, Lan LF, Xue YB and Xu ZH. 2005. OsAGAP, an ARF-GAP from rice, regulates root development dependent mediated by auxin in Arabidopsis. Plant Cell and Environment, 28: 147–156 Xu YY, Wang XM, Li J, Li JH, Wu JS, John C. Walker, Xu ZH and Chong K. 2005. Activation of the WUS gene induces ectopic initiation of foral meristems on mature stem surface in Arabidopsis thaliana. Plant Molecular Biology, 57: 773-784 Ge L, Chen H, Jiang JF, Zhao Y, Xu ML, Xu YY, Tan KH, Xu ZH, and Chong K. 2004. Overexpression of OsRAA1 causes pleiotropic phenotypes in transgenic rice plants, including altered leaf, flower and root development and root response to gravity. Plant Physiology, 135:1502-1513 Yong WD, Xu YY, Xu WZ, Li N, Wu JS, Liang TB, Chong K. Xu ZH and Tan KH. 2003. Vernalization-induced flowering in wheat is mediated by a lectin-like gene VER2. Planta, 217:261-270 出版著作: [1] 许智宏,种康主编,2015,植物细胞分化与器官发生,科学出版社。 [2] 邢立静、徐云远、种康,2012,植物激素在开花中作用,许智宏、薛红卫主编,植物激素作用的分子机理,上海科技出版社。 [3] 徐云远、邢立静、张景昱、种康,2012,植物对低温的响应,陈晓亚、薛红卫主编,植物生理与分子生物学,高等教育出版社。 [4] 种康(译),瞿礼嘉(译),2006,Dieffenbach, Carl W、Dveksler, Gabriela S. 主编:PCR技术实验指南。北京:化学工业出版社。 [5] 种康,王雷,2010,Brassinosteroids and G-protein signaling。Yalovsky S, Baluska F, Jones A主编:Integrated G Proteins Signaling in Plants。Springer. P.135-154。 专利: [1]种康、李丹、黎家、许智宏。一种培育叶夹角改变的转基因水稻的方法及其专用重组载体。中国,授权公告日:2011-11-16,专利号:ZL 200910091548.0 [2]种康、陈苑、陈娜、徐云远。与植物种子大小相关的蛋白及其编码基因与应用。中国,授权公告日2013-08-21,专利号:ZL 201010239549 [3]种康、郭思义、徐云远。microRNA444a或其编码基因在调控水稻分蘖中的应用。中国,授权公告日:2013-10-16,专利号:ZL 201210141053.6 [4]种康、郭思义、徐云远。OsMADS57蛋白或其编码基因在促进水稻分蘖中的应用。中国,授权公告日:2014-03-26,专利号:ZL 201210182988.9 [5]种康、郭思义、徐云远。microRNA444a或其编码基因在调控水稻株高中的应用。中国,授权公告日:2014-03-26,专利号:ZL 201210141051.7 [6]种康、牛遇达、李春华、张景昱。一种小麦遗传转化方法。中国,授权公告日:2014-03-26, 专利号:ZL201210505827.9 [7]种康、郭思义、徐云远。OsMADS57蛋白或其编码基因在抑制水稻分蘖中的应用。中国,授权公告日:2014-07-30, 专利号:201210183051.3 [8]种康、刘唤唤、郭思义、徐云远。microRNA396d或其编码基因在调控水稻开颖中的应用。中国,授权公告日:2014-12-31,专利号:ZL201210140986.3 [9]种康、刘唤唤、郭思义。microRNA396d或其编码基因在调控水稻叶夹角中的应用。中国,授权公告日:2014-12-31,专利号:ZL 201210142346.6 [10]种康、刘唤唤、郭思义、徐云远。microRNA396d或其编码基因在调控水稻株高中的应用。中国,授权公告日:2014-12-31,专利号:ZL 201210142354.0 [11]种康、刘唤唤、郭思义、徐云远、赵原。OsGRF6蛋白在调控植物株高中的应用。中国,授权公告日:2015-03-25,专利号:ZL 201210140837.7 [12]种康、陈丽萍、马岩、郭思义、牛遇达、徐云远。microRNA444a或其编码基因在调节水稻耐盐性中的应用。中国,授权公告日:2016-05-11,专利号:ZL201310009657.X [13]种康、刘栋峰、魏福海、徐云远、张泽勇、罗伟。一种智能高精度低温水浴箱。中国,授权公告日:2017-03-22,专利号:ZL201620970857.0 [14]种康、刘栋峰、罗伟、徐云远、唐永严。一种植物处理装置。中国,授权公告日:2017-10-20,专利号:ZL 201621466511.3 [15]种康、牛遇达、张景昱。一种小麦的快速转化方法。中国,授权公告日:2017-08-17,专利号:ZL 201310632721.X |