邓馨

中国科学院植物研究所

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  • 邓馨
  • 研究员
邓馨,女,博士,研究员,博士生导师。

1993年获黑龙江八一农垦大学学士学位,1996年获沈阳农业大学硕士学位,1999年获中国科学院植物研究所理学博士学位。1999至2003年在德国马普植物育种所进行博士后研究,2005年在德国波恩大学作访问学者,2009至2010年在美国加州大学河滨分校作访问学者。2003年到植物所工作。2006年入选北京市科技新星计划。在Plant and Cell Physiology、Plant Molecular Biology、Frontiers inPlant Science、Planta等SCI收录期刊发表论文40余篇;申请国家发明专利10项,其中5项获得授权。已培养硕士和博士10余名;正在指导博士后2名、博士生和硕士生7名。

主要研究工作:

植物耐旱基因功能与应用;植物逆境生长发育的分子调控;干旱胁迫严重影响植物生长和发育。“复苏植物”在长期的进化过程中形成了独特的适应机制,可以忍耐>95%水分的丧失,并可在重新供水时复苏。为揭示其适应干旱的机理,我们对复苏植物旋蒴苣苔(Boea hygrometrica)展开了系统的组学研究,分析在其耐旱复苏过程中的重要基因和蛋白质,重点研究干旱信号转导途径及与激素调节、气孔调控和渗调保护相关的基因在植物干旱适应和逆境生长发育中的功能和作用机制,发掘抗旱基因资源,创制抗旱植物材料。

主持和参加的科研项目:

[1] “作物适应干旱胁迫的基因转录调控网络”,科技部973项目(2012.01-2016.12),科研骨干。

[2] “玉米转录因子的规模化功能验证”,转基因专项(2011.07-2015.12),科研骨干。

[3] “基于大片段基因组DNA植物表达文库的复苏植物牛耳草耐脱水功能基因组学研究”,国家自然科学基金面上项目(2013.01-2016.01),项目负责人。

[4] “喀斯特地区植物适应高钙方式的多样性及分子基础”,国家自然科学基金面上项目(2010.01-2012.12),项目负责人。

[5] “质膜CYBDOM蛋白促进活性氧产生、侧根发育和抗旱性的机理”,国家自然科学基金面上项目(2015.01-2018.12),项目负责人。

[6] “复苏植物旋蒴苣苔与非复苏植物唇柱苣苔细胞壁差异的分子机理的高通量分析”,科技部中非合作项目(2013.12-2016.12),项目负责人。

[7] “保加利亚与中国的苦苣苔科复苏植物抗脱水机制的比较研究”,科技部中保合作项目(2014.07-2016.07),项目负责人。

研究论文(注*为通讯作者):

2018

Sun RZ*, Lin CT, Zhang XF, Duan LX, Qi XQ, Gong YH, Deng X*. 2018. Acclimation-induced metabolic reprogramming contributes to rapid desiccation tolerance acquisition in Boea hygrometrica. Environ. Exp. Bot., 148: 70-84.

Liu J§, Moyankova D§, Lin CT§, Mladenov P§, Sun RZ, Djilianov D*, Deng X*. 2018. Transcriptome reprogramming during severe dehydration contributes to physiological and metabolic changes in the resurrection plant Haberlea rhodopensis. BMC Plant Biol., 18: 351.(§为共同第一作者)

2017

Wang B, Du H, Zhang ZN, Xu WZ*, Deng X*. 2017. BhbZIP60 from resurrection plant Boea hygrometrica is an mRNA splicing-activated endoplasmic reticulum stress regulator involvedin drought tolerance. Front. Plant Sci., 8: 245.

2016

Lin Sen, Zhao Yuanyuan, Zhu Yingfang, Gosney Michael, Deng Xin, Wang Xiaohua, Lin Jinxing*. 2016. An effective and inducible system of TAL effector-mediated transcriptional repression in Arabidopsis. Molecular Plant, 9(11): 1546-1549.

刘杰, Lin Chih-Ta, 邓馨*. 2016. 复苏植物耐脱水机制研究进展. 生物技术通报, 32(10): 42-51.

2015

Zhu Y, Wang B, Phillips J, Zhang ZN, Du H, Xu T, Huang LC, Zhang XF, Xu GH, Li WL, Wang Z, Wang L, Liu YX, Deng X*. 2015. Global transcriptome analysis reveals acclimation-primed processes involved in the acquisition of desiccation tolerance in Boea hygrometrica.Plant and Cell Physiology, doi: 10.1093/pcp/pcv059

陈世璇,张振南,王波,朱燕*,龚月桦*,孙冬梅,邓馨. 2015. 复苏植物旋蒴苣苔J结构域蛋白编码基因BhDNAJC2的克隆、表达与功能。植物学报,50(2): 180-190

Xiao L, Yang G, Zhang L, Yang X, Zhao S, Ji Z, Zhou Q, Hu M, Wang Y, Chen M, Xu Y, Jin H, Xiao X, Hu G, Bao F, Hu Y, Wan P, Li L, Deng X, Kuang T, Xiang C, Zhu JK*, Oliver MJ*, He Y*. 2015. The resurrection genome of Boea hygrometrica: A blueprint for survival of dehydration. Proc Natl Acad Sci USA. 5,112(18): 5833-5837

2014

Li W, Xu F, Chen S, Zhang Z, Zhao Y, Jin Y, Li M, Zhu Y, Liu Y, Yang Y, Deng X* 2014. A comparative study on Ca content and distribution in two Gesneriaceae species reveals distinctive mechanisms to cope with high rhizospheric soluble calcium. Frontiers in Plant Science, 5: 647

王策,杨艳歌,吕维涛*,周春菊*,孙冬梅,邓馨. 2014. 玉米A亚族bZIP转录因子基因ZmbZIP81的克隆、表达与功能分析。作物学报,40: 1549-1556

张晓飞,段礼新,龚月桦*,邓馨*. 2014. 基于GC-MS的复苏植物牛耳草代谢物提取方法的比较。生物工程学报,30(2): 294-304

Zhao Y, Xu T, Shen CY, Xu GH, Chen SX, Song LZ, Li MJ, Wang LL, Zhu Y, Lv WT, Gong ZZ, Liu CM, Deng X*. 2014. Identification of a retroelement from the resurrection plant Boea hygrometrica that confers osmotic and alkaline tolerance in Arabidopsis thaliana. PLoS ONE, 9(5): e98098, doi:10.1371/journal. pone.0098098

Zhao Y, Shen CY, Xu T, Chen SX, Li WL,Deng X*.2014. A 30-kb genomic DNA fragment of resurrection plant Boea hygrometrica enhances Arabidopsis osmotic and alkaline tolerance.Journal of Food, Agriculture and Environment, 12(1): 210-215

Li WL, Duan HK, Chen FY, Wang Z, Huang XQ, Deng X, Liu YX*.2014. Identification of quantitative trait loci controlling high calcium response in Arabidopsis thaliana. PLoS ONE, 9(11): e112511. doi:10.1371/journal.pone. 0112511

2013

Yang YG, Lv WT, Li MJ, Wang B, Sun DM*,Deng X*. 2013. Maize membrane-bound transcription factor Zmbzip17 is a key regulator in the crosstalk of ER quality control and ABA signaling. Plant and Cell Physiology, 54(12): 2020–2033

Mitra J, Xu G, Wang B, Li M and Deng X*. 2013. Understanding desiccation tolerance using the resurrection plant Boea hygrometrica as a model system. Frontiers in Plant Science,4: 446

杨艳歌,吕维涛,孙冬梅*,凌毅*,邓馨*. 2013. 玉米D亚族bZIP转录因子基因的数据库挖掘、分析、克隆与表达.作物学报,39 (12): 2115-2122

Zhang ZN, Wang B, Sun DM* & Deng X*. 2013. Molecular cloning and differential expression of sHSP gene family members from the resurrection plant Boea hygrometrica in response to abiotic stresses. Biologia , 68( 4)

Wang Z, Cao H, Sun YZ, Li XY, Chen FY, Carles A., Li Y, Ding M, Zhang C, Deng X, Soppe WJJ, Liu YX*. 2013. Arabidopsis paired amphipathic helix proteins SNL1and SNL2 redundantly regulate primary seed dormancy via abscisic acid-ethylene antagonism mediated by histone deacetylation. Plant Cell, 25:149-166.

2012

Duan HK, Zhu Y, Li WL, Qi DD, Liu YX, Deng X*. 2012. Comparative study on the expression of genes involved in carotenoid and ABA biosynthetic pathway in response to salt stress in tomato. Journal of Integrative Agriculture, 11(7): 1093-1102.

Zheng J, Chen FY, Wang Z, Cao H, Li XY, Deng X, Soppe Wim JJ, Li Y and Liu YX*.2012.A novel role for histone methyltransferase KYP?SUVH4 in the control of Arabidopsis primary seed dormancy. New Phytologist 193: 605–616.

2011

王智,刘永秀,魏建华,邓馨*. 2011. 复苏植物牛耳草中棉子糖系列寡糖及棉子糖合酶基因的研究. 植物学报,47(1):44-54

张兰军,姬飞腾,王丽丽,亓岽东,朱燕,邓馨*. 2011. 复苏植物旋蒴苣苔C2结构域小蛋白BhC2DP1以依赖于Ca2+的方式参与植物对ABA的反应. 植物学报,47(1):11-27

Duan HK, Zhu Y, Li WL, Qi DD, Liu YX, Deng X *. 2011. Comparative study on the expression of genes involved in carotenoid and ABA biosynthetic pathway in response to salt stress in tomato. Agricultural Sciences in China, 11(7): 1093-1102

2010以前

Wang Z, Zhu Y, Wang LL, Liu X, Liu YX, Phillips J, Deng X *. 2009. A WRKY transcription factor participates in dehydration tolerance in Boea hygrometrica by binding to the W-box elements of the galactinol synthase (BhGolS1) promoter. Planta, 230: 1155-1166

Zhu Y, Wang Z, Jing YJ, Wang LL, Liu X, Liu YX, Deng X *. 2009. Ectopic over-expression of BhHsf1, a heat shock factor from the resurrection plant Boea hygrometrica, leads to increased thermotolerance and retarded growth in transgenic Arabidopsis and tobacco. Plant Molecular Biology, 71: 451-67

Wang LL, Shang HH, Liu YX, Zheng MZ, Wu RH, Phillips J, Bartels D, Deng X *.2009. A role for a cell wall localized glycine-rich protein in dehydration and rehydration of the resurrection plant Boea hygrometrica. Plant Biology. 11: 837-848

姬飞腾,李楠,邓馨*. 2009. 喀斯特地区植物钙含量特征与高钙适应方式分析. 植物生态学报,33:926-935

Wu RH, Wang LL, Wang Z, Shang HH, Liu X, Zhu Y, Qi DD, Deng X *. 2009. Cloning and expression analysis of a dirigent protein gene from the resurrection plant Boea hygrometrica. Progress in Natural Science, 19: 347-352

Liu X, Wang Z, Wang LL, Wu RH, Phillips J, Deng X *.2008. LEA 4 group genes from the resurrection plant Boea hygrometrica confer dehydration tolerance in transgenic tobacco. Plant Science, 176: 90–98

刘霞,邓馨*. 2008. 复苏植物牛耳草BhLEA2基因启动子的分离和基因表达模式研究. 自然科学进展,19:39-44

吴仁花,王丽丽,王智,商海红,刘霞,朱燕,亓岽东,胡志昂,邓馨*. 2008. 复苏植物牛耳草引导蛋白基因的克隆与表达. 自然科学进展,18:1111-1118

Jiang GQ, Wang Z, Shang HH, Yang WL, Hu ZA, Phillips J, Deng X*. 2007. Proteome analysis of leaves from the resurrection plant Boea hygrometrica in response to dehydration and rehydration. Planta, 225 (6):1405-1420

Deng X, Phillips J, Brautigam A. Engstr?m P, Johannesson H, Ouwerkerk P, Ruberti I, Salinas J, Vera P, Iannacone R, Meijer A, Bartels D*. 2006. A homeodomain leucine zipper gene from Craterostigma plantagineum regulates abscisic acid responsive gene expression and physiological responses. Plant Molecular Biology. 61(3): 469-489

Deng X, Hu ZA*, Wang HX, Wen XG, Kuang TY. 2003. Changes in Photosynthetic Functions of a Resurrection Angiosperm Boea hygrometrica (Bunge) R.Br. (Gesneriaceae) during desiccation and rehydration. Plant Science, 165(4): 851-861

Deng X, Phillips J, Meijer A, Salamini F, Bartels D*. 2002. Characterization of five novel dehydration-responsive homeodomain leucine zipper genes from the resurrection plant Craterostigma plantagineum. Plant Molecular Biology, 49 (6): 601-610.

专利:

[1] 邓馨、朱燕。与植物抗逆相关的热激因子蛋白及其编码基因与应用:中国,ZL200910078056.8.

[2] 邓馨、杨艳歌、吕维涛。转录因子ZmbZIP17及编码基因与其在响应逆境中的应用:中国,ZL201310065802.6.

[3] 邓馨、李美静。一种与植物耐旱相关的蛋白及其编码基因与应用:中国,ZL201310149496.4.

[4] 邓馨、赵燕。植物耐旱耐碱相关的DNA片段及其应用:中国,ZL201210135602.9.

[5] 邓馨、张振南。蛋白BhHSP70-1及其编码基因与应用:中国,ZL201210581636.0.

[6] 邓馨、亓岽东。一种与植物抗旱相关的蛋白及其编码基因与应用:中国,ZL200810023541.5.

[7] 邓馨、马克平、王智、王丽丽。旋蒴苣苔的肌醇半乳糖苷合成酶基因及其编码蛋白与应用:中国,ZL200510112540.X.

[8] 邓馨、马克平、王丽丽、王智、刘霞。一个旋蒴苣苔的抗旱、耐盐相关基因及其编码蛋白与应用:中国,ZL200510127881.4.

[9] 邓馨、王策、吕维涛。OsPYL9蛋白及其编码基因和应用:中国,201310530002.7.

[10] 邓馨、陈世璇。一种可提高植物耐旱盐碱性的蛋白BhDNAJC2及其编码基因与应用:中国,201410176146.1.

[11]邓馨, 陈世璇. 与植物抗逆性相关的蛋白BhDNAJC2及其编码基因与应用. 申请号: 201410176146.1. 授权日期: 2018.07.30.

获奖及荣誉:

邓馨,2006年入选北京市科技新星计划。