赵强

中国科学院生态环境研究中心

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  • 赵强
  • 研究员
  • 北京海淀区双清路18号
简历:

环境化学与生态毒理学国家重点实验室,环境分子识别和传感课题组组长。'国家优秀青年基金'获得者。1996年9月-2000年7月,在北京大学化学与分子工程学院本科学习,获理学学士学位。2000年9月-2005年7月,北京大学化学与分子工程学院直读博士研究生,获分析化学博士学位。2005年9月-2009年7月,在加拿大阿尔伯塔大学临床医学和病理系的分析和环境毒理学部进行博士后研究。2009年9月-2014年7月,山西大学环境科学研究所,教授。2014年7月至今,中国科学院生态环境研究中心,研究员。研究兴趣涉及生物分析和传感,环境分析,新型分析检测技术和方法的发展与应用,新型亲和生物配体的分子识别和分析分离应用,纳米材料的分析传感应用,环境和健康相关蛋白质与小分子的灵敏分析检测和分离,分子识别与相互作用机制研究。

研究方向:

分析化学 环境和生物分析 环境科学

招生方向:
分析化学,环境科学,欢迎分析化学 、环境科学等专业学生报考
专家类别:
高级
职务:
社会任职:
承担科研项目情况:

主持国家自然科学基金优秀青年基金,主持国家自然科学基金面上项目1项,参加国家自然科学基金重点项目1项。

获奖及荣誉:

'国家优秀青年基金'获得者 (2012)

代表论著:

1. R. Dolot, C. H. Lam, M. Sierant, Q. Zhao, F.-W. Liu, B. Nawrot, M. Egli,* X. Yang*, Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity, Nucleic Acids Research , 2018, 46, 4819-4830. 2. L. Sun, Q. Zhao*, Competitive horseradish peroxidase-linked aptamer assay for sensitive detection of aflatoxin B1, Talanta, 2018, 179, 344-349. 3. Y. Bai, Y. Li, D. Zhang, H. Wang, Q. Zhao*, Enhancing the affinity of anti-human α-thrombin 15-mer DNA aptamer and anti-Immunoglobulin E aptamer by polyT extension, Analytical Chemistry, 2017, 89, 9467-9473. 4. Y. Bai, H. Wang, Q. Zhao*, Detection of human neutrophil elastase by aptamer affinity capillary electrophoresis coupled with laser-induced fluorescence using specified site fluorescently labeled aptamer, Analytical Bioanalytical Chemistry, 2017, 409, 6843-6849. ? 5. L. Sun, L. Wu, Q. Zhao*, Aptamer based surface plasmon resonance sensor for aflatoxin B1, Microchimica Acta, 2017, 84, 2605-2610. 6. Y. Li, L. Sun, Q. Zhao* Competitive fluorescence anisotropy/polarization assay for ATP using aptamer as affinity ligand and dye-labeled ATP as fluorescence tracer, Talanta, 2017, 174, 7-13. 7. Y. Liu, Q. Zhao*, Direct fluorescence anisotropy assay for cocaine using tetramethylrhodamine-labeled aptamer, Analytical Bioanalytical Chemistry, 2017, 409, 3993-4000. 8. L. Hao, Y. Bai, H. Wang, Q. Zhao*, Affinity capillary electrophoresis with laser induced fluorescence detection for thrombin analysis using nuclease-resistant RNA aptamers, Journal of Chromatography A, 2016, 1476, 124-129 9. Q. Zhao,* J. Gao, Sensitive and selective detection of thrombin by using a cyclic peptide as affinity ligand, Biosensors Bioelectronics, 2015, 63, 21-25. 10 . Q. Zhao,* Q. Lv, H. Wang, Aptamer fluorescence anisotropy sensors for adenosine triphosphate by comprehensive screening tetramethylrhodamine labeled nucleotides, Biosensors Bioelectronics, 2015, 70, 188-193. 11. Q. Zhao,* Q. Lv, H. Wang, Identification of allosteric nucleotide sites of tetramethylrhodamine-labeled aptamer for noncompetitive aptamer-based fluorescence anisotropy detection of a small molecule, ochratoxin A, Analytical Chemistry, 2014, 86, 1238-1245. 12. Q. Zhao,* J. Gao, An affinity capture involved enzymatic assay for thrombin by using peptide aptamers as affinity ligands on magnetic beads, Chemical Communications, 2013, 49, 7720-7722. 13. Q. Zhao*, X. Geng, H. Wang, Screening interaction between ochratoxin A and aptamers by fluorescence anisotropy approach, Anaytical. Bioanalytical Chemistry 2013, 405, 6281-6286. 14. Q. Zhao*, M. Wu, X.C. Le, X.-F. Li*, Applications of aptamer affinity chromatography, Trends in Analytical Chemistry, 2012, 41, 46-57. 15. Q. Zhao,* X. Wang, An Aptamer-capture based chromogenic assay for thrombin, Biosensors Bioelectronics, 2012, 34, 232-237. 16. Q. Zhao,* X.-F. Li, X. C. Le, Aptamer capturing of enzymes on magnetic beads to enhance assay specificity and sensitivity, Analytical Chemistry, 2011, 83, 9234-9236.