王彦

中国科学院北京生命科学研究院

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  • 王彦
  • 副研究员
  • 北京市朝阳区北辰西路1号院5号 100101
简历:

博士,副研究员。2008年获国家留学基金委资助在美国密西根州立大学访问学习,2010年于中国科学院心理研究所获得博士学位,之后在中国科学院生物物理研究所担任助理研究员;从2013年起加入中国科学院北京生命科学研究院;2017年起任中国科学院北京生命科学研究院副研究员,中国科学院大学硕士生导师。

研究领域:

运用小鼠模型研究外界环境因素影响复杂精神疾病的表观遗传学机制。

代表论著:
Yan Wang#, Cheng Zeng#, Jinchen Li#, Zikai Zhou, Xingda Ju, Shuting Xia, Yuanyuan Li, An Liu, Huajing Teng, Kun Zhang, Leisheng Shi, Cheng Bi, Wei Xie, Xin He, Zhengping Jia, Yonghui Jiang, Tao Cai, Jinyu Wu, Kun Xia, Zhongsheng Sun. PAK2 Haploinsufficiency Results in Synaptic Cytoskeleton Impairment and Autism-Related Behavior.Cell Reports. 2018. August 21, (24): 2029–2041. (F1000Prime Recommended).Yan Wang, Huijie Liu, Zhong Sheng Sun, Lamarck rises from his grave: parental environment-induced epigenetic inheritance in model organisms and humans. Biol Rev Camb Philos Soc. 2017 Nov;92(4):2084–2111. Lin Wang, Zhong Sheng Sun, Bingwu Xiang, Chi?ju Wei, Yan Wang, Kevin Sun, Guanjie Chen, Michael S. Lan, Gilberto N. Carmona, Abner L. Notkins and Tao Cai. Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance. J Transl Med (2018) 16:297. Mei Y, Zhang J, Li Z, Teng H, Wang Y*, Sun Z*. Altered expression of memory genes in food-entrained circadian rhythm. Acta Biochimica et Biophysica Sinica 2018, 50 (10): 1068–1071. Liu Y, Liang Y, Cicek AE, Li Z, Li J, Muhle R, Krenzer M, Mei Y, Wang Y, Knoblauch N, Morrison J, Zhao S, Jiang Y, Geller E, Ionita-Laza I, Wu J, Xia K, Noonan J, Sun ZS, He X. A statistical framework for mapping risk genes from de novo mutations in whole genome sequencing studies. Am J Hum Genet. 2018 Jun 7;102(6):1031–1047.Zhuang Miao, Fengbiao Mao, Jialong Liang, Moshe Szyf,Yan Wang*, Zhong Sheng Sun*. Anxiety-related behaviours associated with microRNA-206-3p and BDNF expression in pregnant female mice following psychological social stress. Molecular Neurobiology (2018). 55(2), 1097–1111. Xiaoting Li#, Yan Wang#, Huan Wang, Tongtong Liu, Jing Guo, Wei Yi, Yan Li. Epithelia-derived Wingless Regulates Dendrite Directional Growth of Drosophila ddaE Neuron through the Fz-Fmi-Dsh-Rac1 Pathway. Molecular brain. 2016 Apr 29;9(1):46. Zhong J, Li X, Cai W, Wang Y, Dong S, Yang J, Zhang J, Wu N, Li Y, Mao F, Zeng C, Wu J, Xu X, Sun ZS. TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair function. Nucleic Acids Res. 2017 Jan 25;45(2):672–684. Yan Wang, Huan Wang, Xiaoting Li, and Yan Li. Epithelial microRNA-9a regulates dendrite growth through Fmi-Gq signaling in Drosophila sensory neurons. Dev Neurobiol.2016 Feb; 76 (2):225–237. Yue Mei, Yan Wang, Huiqian Chen, Zhong Sheng Sun, Xingda Ju. Recent progress in CRISPR/Cas9 technology. Journal of Genetics and Genomics. 2016. Feb 20;43(2):63–75.Zhigang Li#, Yan Wang#, Kevin Kai Sun#, Kangli Wang, Zhong Sheng Sun, Mei Zhao, Jundong Wang. Sex-related difference in food anticipatory activity of mice. Horm Behav. 2015 Apr;70:38–46. Jiesi Wang, Yonglun Luo, Kangli Wang, YanWang, Xiaolin Zhang, Huajing Teng, Zhong Sheng Sun. Clock-controlled StAR's expression and corticosterone production contribute to the endotoxemia immune response.Chronobiology International, 2015 Apr;32(3):358–67. Yan Wang#, Ming Zhang#, Changjong Moon, Qubai Hu, George Martin and Zhongsheng Sun, Hongbing Wang. The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation. Learn Mem. 2009 Aug 27; 16(9):537–44.Yan Wang, Fei Zheng, Xianju Zhou, Zhongsheng Sun and Hongbing Wang. Converging signal on ERK1/2 activity regulates group I mGluR-mediated Arc transcription. Neurosci Lett. 2009 Aug 21; 460(1):36–40.

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