- 关东石
- 副研究员
- 中国科学院力学研究所，非线性力学国家重点实验室（LNM），北京市海淀区北四环西路15号
简历：
2019/01-至今 中国科学院力学研究所，项目研究员
2017/04-2019/01 香港科技大学，物理系，研究助理教授
2016/03-2017/04 香港科技大学，物理系，博士后
2014/03-05，2015/09-12 法国格勒诺布尔大学，访问学者
2010/09-2016/03 香港科技大学，物理系，博士
2006/09-2010/07 北京师范大学，物理系，学士
研究领域：
微纳尺度流动及其在力学交叉学科的应用：微纳尺度下浸润和三相接触线的动力学：钉扎、断裂、迟滞和弛豫；液滴、颗粒、细胞的输运与操控；胶体粒子与界面的相互作用与动力学。软物质与生命物质力学：生命软物质（细胞、组织、相分离蛋白质液滴）多尺度的力学特性；细胞的弹性模量和弛豫模量；细胞在分裂、迁移等生命过程中粘弹性的分布与转变；生物材料和仿生材料的力学性能与机理；聚合物和薄膜的形变、粘弹性和粘附性。原子力显微镜技术的改进与应用：新型悬针式原子力显微镜；胶体探针；液体中软物质材料的形貌表征和力学测量；单细胞的形貌、体积和粘弹性成像；皮牛纳牛尺度力的测量：水动力、静电力、光学力等。
获奖及荣誉：
2017-2019 香港科技大学高等研究院，青年学者 (IAS Junior Fellow)。
代表论著：
(1) 'Reconstituted postsynaptic density as a molecular platform for understanding synapse formation and plasticity,” Menglong Zeng, Xudong Chen, Dongshi Guan, Jia Xu, Haowei Wu, Penger Tong, and Mingjie Zhang, Cell174, 1172 (2018) (Selected as Cell “Best of 2018”).
(2) 'Noncontact viscoelastic imaging of living cells using a long-needle atomic force microscope with duel-frequency modulation,' Dongshi Guan, Elisabeth Charlaix, Robert Z. Qi, and Penger Tong, Physical Review Applied8, 044010 (2017)(Editor’s Suggestion, Featured in Physics, see:Probing Cell Squishiness, Physics10, 117).
(3) 'Noncontact viscoelastic measurement of polymer thin films in a liquid medium using long-needle atomic force microscopy,' Dongshi Guan, Chloé Barraud, Elisabeth Charlaix, and Penger Tong, Langmuir33, 1385-1390 (2017).
(4) 'A simple fabricated thickness-based stiffness gradient for cell studies,' Yiwei Shu, Ho Nam Chan, Dongshi Guan, Lan Ma and Hongkai Wu, Science Bulletin62, 222–228 (2017).
(5) 'Mechanical characterization of microengineered epithelial cysts by using atomic force microscopy,' Yusheng Shen,# Dongshi Guan,# Daniela Serien, Shoji Takeuchi, Penger Tong, Levent Yobas and Pingbo Huang, (# authors contributed equally) Biophysical Journal112, 398–409 (2017).
(6) 'Asymmetric and speed-dependent capillary force hysteresis and relaxation of a suddenly stopped moving contact line,' Dongshi Guan, Yong Jian Wang, Elisabeth Charlaix and Penger Tong, Physical Review Letters116, 066102 (2016).
(7) 'Simultaneous observation of asymmetric speed-dependent capillary force hysteresis and slow relaxation of a suddenly stopped moving contact line,' Dongshi Guan, Yong Jian Wang, Elisabeth Charlaix and Penger Tong, Physical Review E94, 042802 (2016).
(8) 'Direct measurement of optical force induced by near-field plasmonic cavity using dynamic mode AFM,' Dongshi Guan, Zhi Hong Hang, Zsolt Marcet, Hui Liu, I.I. Kravchenko, C. T. Chan, H. B. Chan and Penger Tong, Scientific Reports5, 16216 (2015).
(9) 'The impact of light polarization on imaging visibility of Nth-order intensity correlation with thermal light,' Hongchao Liu, Dongshi Guan, Lu Li, Suheng Zhang, Jun Xiong, Optics Communications283, 405-408, (2010).
(10) 'Effect of Light Polarization on Hanbury Brown-Twiss Experiment,' Lu Li, Dongshi Guan, Hongchao Liu, Suheng Zhang, Jun Xiong, Acta Sinica Quantum Optica3, 002, (2009).
承担科研项目情况：
(1) Experimental study of the volumetric and viscoelastic properties of mitotic cells and their responses to external mechanical cues，General Research Fund (GRF), Research Grants Council (RGC), HKSAR, 主持, 2018-2021.(2) 软物质和生命物质的力学特性与机理研究，中国科学院率先行动“百人计划”, 主持，2019-2022。
