徐明

中国科学院生态环境研究中心

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  • 徐明
  • 副研究员
  • 北京海淀区双清路18号
简历:

2011年毕业于厦门大学、2011年至2013年赴法国国家科学研究院(CNRS)进行博士后研究。一直以典型环境污染污染物为研究对象,包括传统污染物(如重金属)和新型污染物(如高环境暴露风险的纳米材料)。相关研究工作已在国际重要学术期刊上发表SCI论文30余篇,其中在ACS Nano,Analytical Chemistry,Nano Research,Chemistry - A European Journal等期刊发表第一/通讯作者论文15篇,累计被正面引用超过400余次,H index=12。

研究方向:

典型环境污染物的毒理研究

招生方向:
欢迎分析化学、环境科学等专业学生报考
专家类别:
高级
职务:
社会任职:
承担科研项目情况:

参与中国科学院战略性先导科技专项、两项国家重大科学研究计划(973计划)、并主持国家自然科学基金等项目。

获奖及荣誉:
代表论著:

(1) Xu, M.; Mohamed Soliman M. G.; Sun X.; Pelaz B.; Feliu N.; Parak W. J.;* Liu S.* Towards the prediction of protein corona formation and in vitro and in vivo interactions of gold nanoparticles based on their physicochemical properties. ACS Nano 2018, DOI: 10.1021/acsnano.8b04906. (2) Zhu, J.; Xu, M.;* Gao, M.; Zhang, Z.; Xu, Y.; Xia T.; Liu, S.* Graphene Oxide Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents. ACS Nano 2017, 11, 2637-2651. (3) Xu, M.; Zhu, J.; Wang, F.; Xiong, Y.; Wu, Y.; Wang, Q.; Weng, J.;* Zhang, Z.;* Chen, W.; Liu, S.* Improved In Vitro and In Vivo Biocompatibility of Graphene Oxide through Surface Modification: Poly(Acrylic Acid)-Functionalization is Superior to PEGylation. ACS Nano 2016, 10, 3267-3281. (4) Zhu, J.;# Xu, M.;# Wang, F.; Gao, M.; Zhang, Z.; Xu, Y.; Chen, W.; Liu, S. Low-dose exposure of graphene oxide significantly increases metal toxicity to macrophages by altering their cellular priming state. Nano Research, 2018, 11, 4111-4122. (5) Wang, X.; Cheng, W.; Yang, Q.; Niu, H.; Liu, Q.; Liu, Y.; Gao, M.; Xu, M.;* Xu, A.; Liu, S.; Huang, X.;* Du, Y. Preliminary investigation on cytotoxicity of fluorinated polymer nanoparticles. Journal of Environmental Sciences-China, 2018, 69, 217-226. (6) Guo, W.; Zhang, J.; Li, W.; Xu, M.;* Liu, S.* Disruption of iron homeostasis and resultant health effects upon exposure to various environmental pollutants: A critical review. Journal of Environmental Sciences-China, 2015, 34, 155-164. (7) Xu, M.; Yang, L. M.; Wang, Q. Q.* Se-Hg Dual-element Labeling Strategy for Selectively Recognizing Selenoprotein and Selenopeptide. Chinese Journal of Analytical Chemistry, 2015, 43 (9), 1265-1271. (8) Xu, M.; Bijoux H.; Gonzalez P.; Mounicou, S.* Investigating the response of cuproproteins from oysters (Crassostrea gigas) after waterborne copper exposure by metallomic and proteomic. Metallomics, 2014, 6 (2), 338-346. (9) Xu, M.; Frelon, S.; Simon, O.; Lobinski, R.; Mounicou, S.* Non-denaturating isoelectric focusing gel electrophoresis for uranium–protein complexes quantitative analysis with LA-ICP MS. Analytical and Bioanalytical Chemistry, 2014, 406 (4), 1063-1072. (10) Xu, M.; Frelon, S.; Simon, O.; Lobinski, R.; Mounicou, S.* Development of a non-denaturing 2D gel electrophoresis protocol for screening in vivo uranium-protein targets in Procambarus clarkii with laser ablation ICP MS followed by protein identification by HPLC–Orbitrap MS. Talanta, 2014, 128, 187-195. (11) Xu, M.; Yang, L. M.; Wang, Q. Q.* Chemical interactions of mercury species and some transition and noble metals towards metallothionein (Zn7MT-2) evaluated using SEC/ICP-MS, RP-HPLC/ESI-MS and MALDI-TOF-MS. Metallomics, 2013, 5 (7), 855-860. (12) Xu, M.; Yang, L. M.; Wang, Q. Q.* A way to probe the microenvironment of free sulfhydryls in intact proteins with a series of monofunctional organic mercurials. Chemistry - A European Journal, 2012, 18 (44), 13989-13993. (13) Xu, M., Yan, X. W., Xie, Q. Q., Yang, L. M., Wang, Q. Q.* Dynamic labeling strategy with 204Hg-isotopic methylmercurithiosalicylate for absolute peptide and protein quantification. Analytical Chemistry, 82 (5), 1616-1620, 2010. (14) Xu, M., Deng, G. F., Liu, S. S., Chen, S., Cui, D., Yang, L. M., Wang, Q. Q.* Free cadmium ions released from CdTe-based nanoparticles and their cytotoxicity on Phaeodactylum tricornutum. Metallomics, 2 (7), 469-473, 2010. (15) Xu, M., Yang, L. M., Wang, Q. Q.* Quantification of selenium-tagged proteins in human plasma using species-unspecific isotope dilution ICP-DRC-qMS coupled on-line with anion exchange chromatography. Journal of Analytical Atomic Spectrometry, 23 (11), 1545-1549, 2008.