李莉莉

国家纳米科学中心

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1986

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姓       名:
李莉莉
职       务:
职       称: 研究员
通讯地址:

 

简历:

李莉莉,特聘研究员。2012年博士毕业于北京化工大学,2012-2015年在国家纳米科学中心从事博士后科研工作,2015年留任做助理研究员,2017年晋升为副研究员,2018年聘为特聘研究员。主要研究方向为超分子纳米材料的设计制备及重大疾病诊疗应用,围绕体外和体内的超分子可控组装、性能研究以及在肿瘤或感染方面的成像和治疗展开特色研究。近年来,共发表文章28篇,包括Nat Commun, Adv Mater,ACS Nano、Biomaterials、 ACS Appl. Mater. Interfaces等,文章总引用次数超过500次, 相关重要成果多次被MaterialsViewsChina等媒体和学术网站报道。申请国内发明专利三项,国际专利一项,授权一项。以负责人承担科研项目5项,包括自然基金面上、青年等,骨干参与973项目、国际合作项目等6项。2015年度获得国家纳米科学中心主任一等奖和中心纳米青年之星的荣誉称号,2017年成为中国科学院青年促进会成员。研发的抗菌涂层材料应用于陕西省科技统筹创新工程计划资源主导型产业关键技术项目中,为纳米抗菌涂层材料在成果转化方面进行了初步探索。

    个人主页:http://www.escience.cn/people/alisonlilili/index.html

研究领域:

多肽聚合物纳米生物材料设计与合成
“活体自组装”纳米技术在重大疾病诊疗中的应用

获奖及荣誉:

2017 中科院青促会会员

代表论著:

 1.         Qian Cai, Yue Fei, Hong-Wei An, Xiao-Xiao Zhao, Yang Ma, Yong Cong, Liming Hu,* Li-Li Li* and Hao Wang*, Macrophage-Instructed Intracellular S. aureus Killing by Targeting Photodynamic Dimers, ACS Appl. Mater. Interfaces 2018, DOI: 10.1021/acsami.7b19056

 2.         Li-Li Li and Hao Wang, Infection-targeted bactericidal nanoparticles. Nature Biomedical Engineering 2018, 2, 56.

 3.         Li-Li Li†, Sheng-Lin Qiao†, Wei-Jiao Liu, Yang Ma, Dong Wan, Jie Pan, Hao Wang*,Intracellular Construction of Topology-Controlled Polypeptide Nanostructures with Diverse Biological Functions, Nat. Commun., 2017 8, 1276. (†co-first author)

 4.         Sheng-Lin Qiao,†Yang Ma†, Yi Wang, Yao-Xin Lin, Hong-Wei An, Li-Li Li,* and Hao Wang*, A General Approach of Stimuli-Induced-Aggregation for Monitoring Tumor Therapy, ACS Nano, 2017, 11, 7301. (†co-first author)

 5.         Li-Li Li, Xiaodong Li, and Hao Wang*, Microfluidic Synthesis of Nanomaterials for Biomedical Applications , Small Methods, 2017, 1, 1700140.

 6.      Li-Li Li and Hao Wang*, Smart Materials for Tissue Engineering : Fundamental Principles, Eds: Qun Wang, Royal Society of Chemistry., Print ISBN: 978-1-78262-464-6, 2017; 100-123, Chapter 5; Self-assembled Biomaterials for Tissue Engineering.

 7.         Li-Li Li†, Qian Zeng†, Wei-Jiao Liu, Xue-Feng Hu, Yongsheng Li, Jie Pan, Dong Wan, and Hao Wang*, Quantitative Analysis of Caspase-1 Activity in Living Cells Through Dynamic Equilibrium of Chlorophyll-based Nano-Assemblies Modulated Photoacoustic Signals, ACS Appl. Mater. Interfaces 2016, 8, 17936 (†co-first author)

 8.         Li-Li Li†, Huai-Lei Ma†, Guo-bin Qi, Di Zhang, Faquan Yu, Zhi-yuan Hu,* Hao Wang,* Pathological Condition Driven Construction of Supramolecular Nano-Assemblies for Bacterial Infection Detection, Adv. Mater. 2016. 28, 254. VIP Paper (†co-first author)

 9.         Li Li-Li, Wang Hao.* Core–shell supramolecular gelatin nanoparticles for “on demand” antibiotic delivery. J Control. Release. 2015. 213, e71.

 10.     Li-Li Li†, Guo-Bin Qi†, Faquan Yu, Shi-Jie Liu, Hao Wang,* An Adaptive Bio-Interface from Self-Assembled Functional Peptides for Tissue Engineering, Adv. Mater. 2015. 20, 3181 (†co-first author) inside cover

 11.     Li-Li Li†, Jun-Hua Xu†, Guo-Bin Qi, Xingzhong Zhao, Faquan Yu, Hao Wang,* Core–Shell Supramolecular Gelatin Nanoparticles for Adaptive and “On-Demand” Antibiotic Delivery, ACS Nano 2014, 8, 4975 (†co-first author)

 12.     Li-Li Li, Hao Wang,* Enzyme-Coated Mesoporous Silica Nanoparticles as Efficient Antibacterial Agents In Vivo, Adv. Healthcare Mater. 2013, 2, 1351. Inside cover

 13.     Guobin Qi†, Li-Li Li†, Faquan Yu,* Hao Wang,* Vancomycin-modified mesoporous silica nanoparticles for selective recognition and killing of pathogenic gram-positive bacteria over macrophage-like cells, ACS Appl. Mater. Interfaces 2013, 5, 10874. (†co-first author)